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1

Adeno-associated virus (AAV) capsid genes isolated from rat and mouse liver genomic DNA define two new AAV species distantly related to AAV-5

Michael A. Lochrie, Gwen P. Tatsuno, Alejandra E. Arbetman, Kris Jones, Cheryl Pater, Peter H. Smith, Jennifer W. McDonnell, Shang-Zhen Zhou, Shu Kachi, Michiko Kachi, Peter A. Campochiaro, Glenn F. P

Journal:

Year:

2006

Language:

english

File:

PDF, 1.09 MB

english, 2006

2

Increased expression of VEGF in retinal pigmented epithelial cells is not sufficient to cause choroidal neovascularization

Yuji Oshima, Sachiko Oshima, Hiroyuki Nambu, Shu Kachi, Sean F. Hackett, Michele Melia, Michael Kaleko, Sheila Connelly, Noriko Esumi, Donald J. Zack, Peter A. Campochiaro

Journal:

Journal of Cellular Physiology

Year:

2004

Language:

english

File:

PDF, 331 KB

english, 2004

3

Angiopoietin 1 prevents retinal detachment in an aggressive model of proliferative retinopathy, but has no effect on established neovascularization

Hiroyuki Nambu, Naoyasu Umeda, Shu Kachi, Yuji Oshima, Hideo Akiyama, Rie Nambu, Peter A. Campochiaro

Journal:

Journal of Cellular Physiology

Year:

2005

Language:

english

File:

PDF, 450 KB

english, 2005

4

Intraocular injection of an aptamer that binds PDGF-B: A potential treatment for proliferative retinopathies

Hideo Akiyama, Shu Kachi, Raquel Lima E Silva, Naoyasu Umeda, Sean F. Hackett, Dilara McCauley, Thomas McCauley, Anna Zoltoski, David M. Epstein, Peter A. Campochiaro

Journal:

Journal of Cellular Physiology

Year:

2006

Language:

english

File:

PDF, 214 KB

english, 2006

5

Recombinant non-collagenous domain of α2(IV) collagen causes involution of choroidal neovascularization by inducing apoptosis

Raquel Lima e Silva, Shu Kachi, Hideo Akiyama, JiKui Shen, Sadia Aslam, Yuan Yuan Gong, Naw Htee Khu, Maria C. Hatara, Ariel Boutaud, Robert Peterson, Peter A. Campochiaro

Journal:

Journal of Cellular Physiology

Year:

2006

Language:

english

File:

PDF, 254 KB

english, 2006

6

Reduction of p66Shc suppresses oxidative damage in retinal pigmented epithelial cells and retina

Zhihao Wu, Brian Rogers, Shu Kachi, Sean F. Hackett, Anna Sick, Peter A. Campochiaro

Journal:

Journal of Cellular Physiology

Year:

2006

Language:

english

File:

PDF, 401 KB

english, 2006

7

Topical administration of a multi-targeted kinase inhibitor suppresses choroidal neovascularization and retinal edema

John Doukas, Sankaranarayana Mahesh, Naoyasu Umeda, Shu Kachi, Hideo Akiyama, Katsutoshi Yokoi, Jon Cao, Zoe Chen, Luis Dellamary, Betty Tam, Adrienne Racanelli-Layton, John Hood, Michael Martin, Glen

Journal:

Journal of Cellular Physiology

Year:

2008

Language:

english

File:

PDF, 353 KB

english, 2008

8

Corneal and Macular Manifestations in a Case of Deficient Lecithin: Cholesterol Acyltransferase

Koji Hirano, Shu Kachi, Chika Ushida, Michitaka Naito

Journal:

Japanese Journal of Ophthalmology

Year:

2004

Language:

english

File:

PDF, 169 KB

english, 2004

9

Periocular Gene Transfer of Pigment Epithelium-Derived Factor Inhibits Choroidal Neovascularization in a Human-Sized Eye

Saishin, Yoshitsugu, Silva, Raquel Lima, Saishin, Yumiko, Kachi, Shu, Aslam, Sadia, Gong, Yuan Yuan, Lai, Hong, Carrion, Miguel, Harris, Brent, Hamilton, Melissa

Journal:

Human Gene Therapy

Year:

2005

Language:

english

File:

PDF, 235 KB

english, 2005

10

Retinal degeneration from oxidative damage

Celia Cingolani, Brian Rogers, Lili Lu, Shu Kachi, JiKui Shen, Peter A. Campochiaro

Journal:

Free Radical Biology and Medicine

Year:

2006

Language:

english

File:

PDF, 574 KB

english, 2006

11

Detailed Localization of Photoreceptor Guanylate Cyclase Activating Protein-1 and -2 in Mammalian Retinas using Light and Electron Microscopy

SHU KACHI, YUJI NISHIZAWA, ELENA OLSHEVSKAYA, AKIO YAMAZAKI, YOZO MIYAKE, TAKASHI WAKABAYASHI, ALEXANDER DIZHOOR, JIRO USUKURA

Journal:

Experimental Eye Research

Year:

1999

Language:

english

File:

PDF, 821 KB

english, 1999

12

Trans-scleral delivery of polyamine analogs for ocular neovascularization

Raquel Lima e Silva, Shu Kachi, Hideo Akiyama, JiKui Shen, Maria Christina Hatara, Sadia Aslam, Yuan Yuan Gong, Naw Htee Khu, Thomas W. Lauer, Sean F. Hackett, Laurence J. Marton, Peter A. Campochiaro

Journal:

Experimental Eye Research

Year:

2006

Language:

english

File:

PDF, 509 KB

english, 2006

13

Ultrastructure of internal limiting membrane removed during plasmin-assisted vitrectomy from eyes with diabetic macular edema

Tetsu Asami, Hiroko Terasaki, Shu Kachi, Makoto Nakamura, Keiko Yamamura, Toshitaka Nabeshima, Yozo Miyake

Journal:

Year:

2004

Language:

english

File:

PDF, 468 KB

english, 2004

14

Author reply

Tetsu Asami, Hiroko Terasaki, Shu Kachi, Makoto Nakamura, Keiko Yamamura, Toshitaka Nabeshima, Yozo Miyake

Journal:

Year:

2004

Language:

english

File:

PDF, 40 KB

english, 2004

15

Unusual corneal deposit after the topical use of cyclosporine as eyedrops

Shu Kachi, Koji Hirano, Yoshiko Takesue, Masanori Miura

Journal:

American Journal of Ophthalmology

Year:

2000

Language:

english

File:

PDF, 283 KB

english, 2000

16

Histamine H 4 receptor as a new therapeutic target for choroidal neovascularization in age-related macular degeneration

Kaneko, Hiroki, Ye, Fuxiang, Ijima, Ryo, Kachi, Shu, Kato, Seiichi, Nagaya, Masatoshi, Higuchi, Akiko, Terasaki, Hiroko

Journal:

British Journal of Pharmacology

Year:

2014

Language:

english

File:

PDF, 1004 KB

english, 2014

17

Electroretinograms and level of aqueous vascular endothelial growth factor in eyes with hemicentral retinal vein occlusion or branch retinal vein occlusion

Yasuda, Shunsuke, Kachi, Shu, Ueno, Shinji, Ushida, Hiroaki, Piao, Chang-Hua, Kondo, Mineo, Terasaki, Hiroko

Journal:

Japanese Journal of Ophthalmology

Year:

2014

Language:

english

File:

PDF, 261 KB

english, 2014

18

Development of Prodrug 4-Chloro-3-(5-methyl-3-{[4-(2-pyrrolidin-1-ylethoxy)phenyl]amino}-1,2,4-benzotriazin-7-yl)phenyl Benzoate (TG100801): A Topically Administered Therapeutic Candidate in Clinical Trials for the Treatment of Age-Related Macular Degeneration

Palanki, Moorthy S. S., Akiyama, Hideo, Campochiaro, Peter, Cao, Jianguo, Chow, Chun P., Dellamary, Luis, Doukas, John, Fine, Richard, Gritzen, Colleen, Hood, John D., Hu, Steven, Kachi, Shu, Kang, Xi

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 669 KB

english, 2008

19

788. Engineered Zinc Finger Protein Transcription Factors as a Potential Therapy for Choroidal Neovascularization

Zhang, Steve, Kachi, Shu, Hackett, Sean F., Kachi, Michido, Akiyama, Hideo, Umeda, Naoyasu, Yokoi, Katsutoshi, Liu, Pei-qi, Veres, Gabor, Gregory, Philip D., Campochiaro, Peter A.

Journal:

Molecular Therapy

Year:

2006

Language:

english

File:

PDF, 89 KB

english, 2006

20

Differential Sensitivity of Cones to Iron-Mediated Oxidative Damage

Rogers, Brian S., Symons, Robert C. A., Komeima, Keiichi, Shen, JiKui, Xiao, Weihong, Swaim, Mara E., Gong, Yuan Yuan, Kachi, Shu, Campochiaro, Peter A.

Journal:

Investigative Ophthalmology & Visual Science

Year:

2007

Language:

english

File:

PDF, 697 KB

english, 2007

21

Retardation of Photoreceptor Degeneration in the Detached Retina of rd1 Mouse

Kaneko, Hiroki, Nishiguchi, Koji M., Nakamura, Makoto, Kachi, Shu, Terasaki, Hiroko

Journal:

Investigative Ophthalmology & Visual Science

Year:

2008

Language:

english

File:

PDF, 675 KB

english, 2008

22

Suppression and Regression of Choroidal Neovascularization by Polyamine Analogues

Silva, Raquel Lima e, Saishin, Yoshitsugu, Saishin, Yumiko, Akiyama, Hideo, Kachi, Shu, Aslam, Sadia, Rogers, Brian, Deering, Tye, Gong, Yuan Yuan, Hackett, Sean F., Lai, Hong, Frydman, Benjamin J., V

Journal:

Investigative Ophthalmology & Visual Science

Year:

2005

Language:

english

File:

PDF, 501 KB

english, 2005

23

Identification of Photoreceptor Precursors in the Pars Plana during Ocular Development and after Retinal Injury

Nishiguchi, Koji M., Kaneko, Hiroki, Nakamura, Makoto, Kachi, Shu, Terasaki, Hiroko

Journal:

Investigative Ophthalmology & Visual Science

Year:

2008

Language:

english

File:

PDF, 852 KB

english, 2008

24

Ocular Gene Transfer with Self-Complementary AAV Vectors

Yokoi, Katsutoshi, Kachi, Shu, Zhang, H. Steve, Gregory, Philip D., Spratt, S. Kaye, Samulski, R. Jude, Campochiaro, Peter A.

Journal:

Investigative Ophthalmology & Visual Science

Year:

2007

Language:

english

File:

PDF, 282 KB

english, 2007

25

Influence of Preoperative Intravitreal Bevacizumab on Visual Function in Eyes with Proliferative Diabetic Retinopathy

Ushida, Hiroaki, Kachi, Shu, Asami, Tetsu, Ishikawa, Kohei, Kondo, Mineo, Terasaki, Hiroko

Journal:

Ophthalmic Research

Year:

2013

Language:

english

File:

PDF, 782 KB

english, 2013

26

Characteristics of Bone Marrow–Derived Microglia in the Normal and Injured Retina

Kaneko, Hiroki, Nishiguchi, Koji M., Nakamura, Makoto, Kachi, Shu, Terasaki, Hiroko

Journal:

Investigative Ophthalmology & Visual Science

Year:

2008

Language:

english

File:

PDF, 1.02 MB

english, 2008

27

Preservation of Macular Oscillatory Potentials in Eyes of Patients with Retinitis Pigmentosa and Normal Visual Acuity

Ikenoya, Kazuteru, Kondo, Mineo, Piao, Chang-Hua, Kachi, Shu, Miyake, Yozo, Terasaki, Hiroko

Journal:

Investigative Ophthalmology & Visual Science

Year:

2007

Language:

english

File:

PDF, 203 KB

english, 2007

28

Equine Infectious Anemia Viral Vector-Mediated Codelivery of Endostatin and Angiostatin Driven by Retinal Pigmented Epithelium-Specific VMD2 Promoter Inhibits Choroidal Neovascularization

Kachi, Shu, Binley, Katie, Yokoi, Katsutoshi, Umeda, Naoyasu, Akiyama, Hideo, Muramatu, Daisuke, Iqball, Sharifah, Kan, On, Naylor, Stuart, Campochiaro, Peter A.

Journal:

Human Gene Therapy

Year:

2009

Language:

english

File:

PDF, 37.12 MB

english, 2009

29

Buckling surgery and supplemental intravitreal bevacizumab or photocoagulation on stage 4 retinopathy of prematurity eyes

Futamura, Yukiko, Asami, Tetsu, Nonobe, Norie, Kachi, Shu, Ito, Yasuki, Sato, Yoshiaki, Hayakawa, Masahiro, Terasaki, Hiroko

Journal:

Japanese Journal of Ophthalmology

Year:

2015

Language:

english

File:

PDF, 832 KB

english, 2015

30

Expression of Vascular Endothelial Growth Factor by Retinal Pigment Epithelial Cells Induced by Amyloid-� Is Depressed by an Endoplasmic Reticulum Stress Inhibitor

Matsui, Asako, Kaneko, Hiroki, Kachi, Shu, Ye, Fuxiang, Hwang, Shiang-Jyi, Takayama, Kei, Nagasaka, Yosuke, Sugita, Tadasu, Terasaki, Hiroko

Journal:

Ophthalmic Research

Year:

2015

Language:

english

File:

PDF, 289 KB

english, 2015

31

Triamcinolone-Assisted Removal of Internal Limiting Membrane Enhances the Effect of Vitrectomy for Diabetic Macular Edema

Yamakoshi, Tomomi, Kachi, Shu, Sugita, Jiro, Asami, Tetsu, Ishikawa, Kohei, Ito, Yasuki, Terasaki, Hiroko

Journal:

Ophthalmic Research

Year:

2009

Language:

english

File:

PDF, 232 KB

english, 2009

32

Ultrasonographic Biomicroscopic Study of an Intracorneal Hematoma

Kachi, Shu, Hirano, Koji

Journal:

Year:

2002

Language:

english

File:

PDF, 410 KB

english, 2002

33

ACQUIRED UNILATERAL NIGHT BLINDNESS WITH NEGATIVE ERG: NINE-YEAR FOLLOW-UP

KONDO, MINEO, NAKAMURA, MAKOTO, TANIKAWA, ATSUHIRO, KACHI, SHU, HIRAI, TOSHIE, MIYAKE, YOZO

Journal:

Year:

2005

Language:

english

File:

PDF, 3.57 MB

english, 2005

34

Optical Coherence Tomography for the Noninvasive Evaluation of the Cornea

Hirano, Koji, Ito, Yasuki, Suzuki, Toshimitsu, Kojima, Takeshi, Kachi, Shu, Miyake, Yozo

Journal:

Year:

2001

Language:

english

File:

PDF, 5.82 MB

english, 2001

35

CONCENTRATION OF VASCULAR ENDOTHELIAL GROWTH FACTOR IN AQUEOUS HUMOR OF EYES WITH ADVANCED RETINOPATHY OF PREMATURITY BEFORE AND AFTER INTRAVITREAL INJECTION OF BEVACIZUMAB

NONOBE, NORIE ITO, KACHI, SHU, KONDO, MINEO, TAKAI, YOSHIKO, TAKEMOTO, KOJI, NAKAYAMA, ATSUSHI, HAYAKAWA, MASAHIRO, TERASAKI, HIROKO

Journal:

Year:

2009

Language:

english

File:

PDF, 963 KB

english, 2009

36

REBOUND OF MACULAR EDEMA AFTER INTRAVITREAL BEVACIZUMAB THERAPY IN EYES WITH MACULAR EDEMA SECONDARY TO BRANCH RETINAL VEIN OCCLUSION

Yasuda, Shunsuke, Kondo, Mineo, Kachi, Shu, Ito, Yasuki, Terui, Takayuki, Ueno, Shinji, Terasaki, Hiroko

Journal:

Year:

2011

Language:

english

File:

PDF, 443 KB

english, 2011

37

Flicker electroretinograms before and after intravitreal ranibizumab injection in eyes with central retinal vein occlusion

Yasuda, Shunsuke, Kachi, Shu, Ueno, Shinji, Piao, Chang-Hua, Terasaki, Hiroko

Journal:

Acta Ophthalmologica (Blackwell)

Year:

2015

Language:

english

File:

PDF, 459 KB

english, 2015

38

Reply

Kondo, Mineo, Ito, Yasuki, Kachi, Shu, Kikuchi, Masato, Yasuma, Tetsuhiro R., Terasaki, Hiroko, Kondo, Nagako, Ota, Ichiro, Miyake, Kensaku

Journal:

Year:

2010

Language:

english

File:

PDF, 70 KB

english, 2010

39

INTRAVITREAL INJECTION OF BEVACIZUMAB FOR MACULAR EDEMA SECONDARY TO BRANCH RETINAL VEIN OCCLUSION

KONDO, MINEO, KONDO, NAGAKO, ITO, YASUKI, KACHI, SHU, KIKUCHI, MASATO, YASUMA, TETSUHIRO R., OTA, ICHIRO, MIYAKE, KENSAKU, TERASAKI, HIROKO

Journal:

Year:

2009

Language:

english

File:

PDF, 573 KB

english, 2009

40

ACUTE RETINAL NECROSIS AFTER CORTICOSTEROID PULSE THERAPY FOR UNILATERAL VOGT-KOYANAGI-HARADA DISEASE

Yokoi, Reiko, Asami, Tetsu, Kachi, Shu, Ito, Yasuki, Nakamura, Makoto, Terasaki, Hiroko

Journal:

Retinal Cases & Brief Reports

Year:

2010

Language:

english

File:

PDF, 1.72 MB

english, 2010

41

Gene Transfer of An Engineered Zinc Finger Protein Enhances the Anti-angiogenic Defense System

Yokoi, Katsutoshi, Zhang, Huanda Steve, Kachi, Shu, Balaggan, Kamaljit S, Yu, Qi, Guschin, Dmitry, Kunis, Mike, Surosky, Richard, Africa, Liza M, Bainbridge, James W, Spratt, Sharon Kaye, Gregory, Phi

Journal:

Molecular Therapy

Year:

2007

Language:

english

File:

PDF, 372 KB

english, 2007

42

Novel OPN1LW/OPN1MW deletion mutations in 2 Japanese families with blue cone monochromacy

Wang, Chunxia, Hosono, Katsuhiro, Kachi, Shu, Suto, Kimiko, Nakamura, Makoto, Terasaki, Hiroko, Miyake, Yozo, Hotta, Yoshihiro, Minoshima, Shinsei

Journal:

Human Genome Variation

Year:

2016

Language:

english

File:

PDF, 1.20 MB

english, 2016

43

Regulation of Pathologic Retinal Angiogenesis in Mice and Inhibition of VEGF-VEGFR2 Binding by Soluble Heparan Sulfate

Nishiguchi, Koji M., Kataoka, Keiko, Kachi, Shu, Komeima, Keiichi, Terasaki, Hiroko, Morty, Rory Edward

Journal:

Year:

2010

Language:

english

File:

PDF, 6.04 MB

english, 2010

44

Interleukin-18 Induces Retinal Pigment Epithelium Degeneration in Mice

Ijima, Ryo, Kaneko, Hiroki, Ye, Fuxiang, Nagasaka, Yosuke, Takayama, Kei, Kataoka, Keiko, Kachi, Shu, Iwase, Takeshi, Terasaki, Hiroko

Journal:

Investigative Opthalmology & Visual Science

Year:

2014

File:

PDF, 519 KB

2014

45

Suppression of Choroidal Neovascularization and Quantitative and Qualitative Inhibition of VEGF and CCL2 by Heparin

Tomida, Daisuke, Nishiguchi, Koji M., Kataoka, Keiko, Yasuma, Tetsuhiro R., Iwata, Eiji, Uetani, Ruka, Kachi, Shu, Terasaki, Hiroko

Journal:

Investigative Ophthalmology & Visual Science

Year:

2011

Language:

english

File:

PDF, 1.48 MB

english, 2011

46

The Roles of Vitreal Macrophages and Circulating Leukocytes in Retinal Neovascularization

Kataoka, Keiko, Nishiguchi, Koji M., Kaneko, Hiroki, van Rooijen, Nico, Kachi, Shu, Terasaki, Hiroko

Journal:

Investigative Ophthalmology & Visual Science

Year:

2011

Language:

english

File:

PDF, 4.77 MB

english, 2011

47

Interleukin-18 Induces Retinal Pigment Epithelium Degeneration in Mice

Ijima, Ryo, Kaneko, Hiroki, Ye, Fuxiang, Nagasaka, Yosuke, Takayama, Kei, Kataoka, Keiko, Kachi, Shu, Iwase, Takeshi, Terasaki, Hiroko

Journal:

Investigative Opthalmology & Visual Science

Year:

2014

Language:

english

File:

PDF, 519 KB

english, 2014

48

Suppression of Laser-Induced Choroidal Neovascularization by the Oral Medicine Targeting Histamine Receptor H4 in Mice

Ijima, Ryo, Kaneko, Hiroki, Ye, Fuxiang, Takayama, Kei, Nagasaka, Yosuke, Kataoka, Keiko, Funahashi, Yasuhito, Iwase, Takeshi, Kachi, Shu, Kato, Seiichi, Terasaki, Hiroko

Journal:

Translational Vision Science & Technology

Year:

2015

Language:

english

File:

PDF, 653 KB

english, 2015

49

Role of Caveolin-1 for Blocking the Epithelial-Mesenchymal Transition in Proliferative Vitreoretinopathy

Nagasaka, Yosuke, Kaneko, Hiroki, Ye, Fuxiang, Kachi, Shu, Asami, Tetsu, Kato, Seiichi, Takayama, Kei, Hwang, Shiang-Jyi, Kataoka, Keiko, Shimizu, Hideyuki, Iwase, Takeshi, Funahashi, Yasuhito, Higuch

Journal:

Investigative Opthalmology & Visual Science

Year:

2017

Language:

english

File:

PDF, 1.03 MB

english, 2017

50

Significant Correlation between Electroretinogram Parameters and Ocular Vascular Endothelial Growth Factor Concentration in Central Retinal Vein Occlusion Eyes

Yasuda, Shunsuke, Kachi, Shu, Kondo, Mineo, Ushida, Hiroaki, Uetani, Ruka, Terui, Takayuki, Piao, Chang-Hua, Terasaki, Hiroko

Journal:

Investigative Ophthalmology & Visual Science

Year:

2011

Language:

english

File:

PDF, 457 KB

english, 2011

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